woman scientist in a lab testing matrials

New Study Shows 2-HOBA Supports Immune Function

April 10, 2023
No Comments

a line of test tubes with blood in them
NEW Study Shows 2-HOBA Supplementation has a Promising Impact on Immune Health.

TSI Group is proud to announce positive results from a recent NIH-funded study on the impact of 2-hydroxybenzylamine (2-HOBA), TSI’s branded ingredient Hobamine, on inflammatory biomarkers.

Balance is Essential to a Proactive Approach to Immune Health

The NIH-funded study, published in the journal Inflammation, found that supplementing with 2-HOBA improved as many as 15 inflammatory biomarkers in healthy individuals, thereby promoting a healthy balance of the immune system.

“Normally, inflammation is self-limiting, and its resolution is the first step in the repair and regeneration of injured tissues. Failure of inflammation resolution can lead to the progression of several diseases,” says John A. Rathmacher, Ph.D., Director of Clinical Research and Laboratory Services at MTI BioTech, Inc. That’s why a balanced immune system is incredibly important.

Opportunities for Immune Formulations

“These results enable us to enter a new space in immune health and will guide us in future research,” comments TSI Group Vice President of Business Development Shawn Baier, M.S., M.B.A. “More significantly, this opens opportunities for formulators and developers to add Hobamine to their immune formulas because it clearly enables healthy individuals to be more proactive about maintaining their immune readiness.”

This concept of immune readiness is perhaps what Baier finds most exciting. “If you don’t have 2-HOBA present, and your body creates these highly-reactive, proinflammatory compounds, it could begin an unhealthy snowball effect. Having 2-HOBA on board means it’s ready and there when it’s needed. It supports your immune system’s ability to stay in balance, even when you are exposed to oxidative stressors.”

Read the study or correlating articles below.

arrow-icon-size3 Read the Study
arrow-icon-size3 Nutraceuticals World Article
arrow-icon-size3 Nutrition Insight Article
arrow-icon-size3 Whole Foods Magazine Article

Read More

white pill bottle with tan background and two tan/brown capsules coming out of the pill bottle

2-HOBA for Cellular Health

March 24, 2023
No Comments

wood table with 4 capsules containing brown powder inside and a white pill bottle subtle in the background

TSI Group’s new compound, Hobamine (2-HOBA) has shown to support cellular health through a unique mechanism.

As science continues to advance, looking at health at a cellular level has more prominant. 

“Cellular health matters because it has an important impact on how well our bodies function, repair themselves, produce new body tissue, and much more,” according to Shawn Baier, vice president of business development with TSI Group’s Innovative Products Division. “As we all know, our immune system and how it responds to various stimuli has an effect on our cellular health, both positively and negatively. Cells form tissues, tissues form organs, and organs form systems that make up the body. Cellular health is the microscopic version of overall health—the healthier our cells, the healthier our body will be since our cells will be working optimally and efficiently with one another. “


A Radical Approach to Cellular Health

Oxidative stress is the primary cause of cellular damage. Excessive oxidative stress causes a buildup of a specific class of free radicals that can cause harm to the body.  Unfortunately, it’s merely impossible to eliminate all oxidative stress from our lives because of factors such as environment, poor nutrition, excess alcohol, lack of sleep, stress, and/or simply aging.

Hobamine (2-HOBA), a bio-identical, chemically synthesized version of the naturally occurring compound 2-hydroxybenzylamine (2-HOBA) found in the buckwheat plant can help combat oxidative stress.  What makes Hobamine unique or even radical is that it works by acting specifically against compounds responsible for oxidative damage without blocking the processes needed for healthy cell function. 

“Hobamine (2-HOBA) represents a paradigm shift in the approach to reducing the impact of oxidative stress because it is a selective scavenger of high-impact reactive oxygen species (ROS), specifically isolevuglandins (IsoLGs), but doesn’t interfere with or blunt fundamental physiological processes,” said Baier. “Therefore, 2-HOBA helps to return the healthy balance our cells and bodies need.”

To read the full article feature in Nutraceuticals World please follow the link below.

arrow-icon-size3 Full Article

Read More