Newsroom - Hobamine®

Oxidative Stress and Cellular Health: How Hobamine® (2-HOBA) Supports a Targeted Defense

Oxidative stress and cellular health are now central topics in conversations around long-term health, healthy aging, and cellular resilience. The reason is simple: these processes can influence how well our cells function over time. The body is built to manage everyday stressors. In fact, oxidative stress is a normal part of life and metabolism. But when that balance is disrupted, harmful downstream compounds can build up and can bind to proteins, lipids, and DNA; creating a negative impact. That is where a more targeted approach to cellular health becomes important. Hobamine® (2-hydroxybenzylamine or 2-HOBA) is designed to support cellular health by capturing specific damaging

A Targeted Scavenging Approach to Supporting Cellular Balance Under Oxidative Stress

Oxidative stress is a normal outcome of metabolic activity, immune function, and environmental exposure. The body has built-in systems to manage these processes, but when downstream reactions become excessive or poorly controlled, they can place added strain on cellular balance. As scientific understanding continues to evolve, interest is moving away from broad suppression strategies and toward more precise approaches that support normal cellular function while addressing the compounds most responsible for oxidative stress. This shift was recently reflected in an industry discussion published by Nutrition Industry Executive, where Hobamine® (2-HOBA) was mentioned for its role in addressing oxidative stress through selective scavenging. Oxidative Stress and Downstream Reactive Compounds Oxidative stress

Hobamine is an innovative ingredient that promotes cell health.

Unique Ingredient Hobamine® Receives Health Canada NPN Approval

A Groundbreaking Step for Cellular Health in Canada TSI Group’s innovative cellular health ingredient, Hobamine®, has received a Natural Product Number (NPN) #80138909 from Health Canada’s Natural and Non-Prescription Health Products Directorate (NNHPD). This marks the first-ever NPN issued in Canada for a 2-HOBA ingredient, signifying its approval for sale in the Canadian market. Hobamine®, a specialized form of the naturally occurring compound 2-HOBA, is now officially recognized for its ability to help cells protect against oxidative damage caused by free radicals.* The recommended adult dosage is one capsule, twice daily. NPN – A Milestone in Innovation “Receiving an NPN

Hobamine® Supports Resilience at the Cellular Level

A recent article from PricePlow explores how Hobamine® (2-HOBA) plays a unique role in protecting the body from oxidative stress while supporting immune health and healthy aging at the cellular level. As research into healthy aging and immune support evolves, Hobamine® continues to stand out for its precise and targeted benefits. What is Hobamine®? Hobamine® (2-hydroxybenzylamine acetate or 2-HOBA) is a naturally occurring compound involved at the cellular level. It targets and neutralizes reactive dicarbonyl electrophiles, such as isolevuglandins (IsoLGs) — harmful byproducts of lipid peroxidation that can damage DNA, proteins, and cell membranes. This precision-based action makes Hobamine®

Revolutionizing Healthy Aging with a Focus on Cellular Health

The focus on healthspan over lifespan is transforming the healthy aging landscape, with consumers taking a proactive and holistic approach to their golden years. This evolution in behavior is driving demand for innovative products that support physical, mental, and cellular health. The SupplySide Supplement Journal Product Development Guide delves into the latest trends and strategies, offering brands a roadmap to thrive in this growing market, which is expected to expand by 8.5% by 2027. With a shift from “anti-aging” to “healthy aging,” today’s products appeal to multigenerational consumers, from Boomers to Gen Z, who seek solutions that promote long-term well-being.

A Year in Review

Hobamine has claimed the spotlight in the field of cellular health this past year, and TSI Group eagerly anticipates the developments in 2024. Hobamine, TSI Group’s latest ingredient breakthrough, has garnered recognition as one of the standout discoveries of the year. As we take pride in reflecting on the past year, we eagerly anticipate exploring new studies and findings that await on the horizon. But first, let’s revisit some notable highlights from 2023. New Study Shows 2-HOBA has a Promising Impact on Immune Health In a study funded by the NIH and published in the journal Inflammation, it

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The Importance of Immune Health

In Nutraceuticals World an article Immune Health Remains a Top Priority, Even as Many Move on from Covid, highlights the importance of immune health and how new supplement formulas offer great value to consumers. Despite a 4.3% decline in sales for immune health supplements in the last year, the category remains relevant. The decline is slowing, and experts believe it won’t plummet to the levels seen after the pandemic’s peak. One significant challenge faced by manufacturers, vendors, and retailers is dealing with overstock issues as they stocked up on immune products during the pandemic. However, this overstock situation has opened

The Cellular Health Market

In Nutritional Outlook, industry leaders give their expert advice on the trends that are driving the cellular health market. The cellular health industry continues to grow with more and more ingredients coming to the forefront. As this category evolves, it’s hard for consumers to navigate the market. Brands need to step up their game to educate consumers on the science behind these ingredients. New Developments in Cellular Health “Aging research has evolved in recent years,” says Aileen Stocks, president of wellness brands at Nestlé Health Science. “Researchers now know there is a time-related decline of several cellular mechanisms that often

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A Proactive Approach to Aging

We all want to live our best lives even as we age. In The Natural View podcast with Todd Pauli and Maggie Jaqua, they have special guest Shawn Baier, VP of Business Development at TSI Group, to discuss healthy aging, overlooked component, and nutritional ingredients to promote healthy aging. Healthy, Active Aging There are many various categories to focus on when we talk about healthy aging like joints, bones, and cognitive health. One area that tends to get overlooked when it comes to healthy aging is muscle health. Unfortunately, we will all experience age-related muscle loss and if not

3 Ingredients to Support Health & Performance

At SupplySide East experts discuss what ingredients they believe people should be supplementing with to support sports performance and overall health. Todd Runestad, Natural Products Insider content director spoke with Douglas S. Kalman, Ph.D., clinical associate professor at Nova Southeastern University in Florida to gain his expert insight on the top three ingredients that are effective in the sports nutrition arena. According to Kalman, his top 3 ingredients were Hobamine, HMB, and Creatine. Here is a little insight on why he chose these 3 ingredients. Hobamine Our lives are filled of stress and high-intensity exercise also induces stress on the

Hobamine – NutraIngredients USA Awards Winner!

TSI Group is proud to announce that 2023 Nutrition Research Project of the Year Award from NutraIngredients-USA goes to the NIH-funded Hobamine study. NutraIngredients-USA Awards persist in acknowledging excellence within the dietary supplement industry. With 17 different categories to enter, the awards honor the best and brightest ingredients, finished products, companies and people in the nutrition industry. Hobamine’s Award Winning Study The new NIH-funded study on Hobamine, Inflammation Biomarker Response to Oral 2-Hydroxybenzylamine (2-HOBA) Acetate in Healthy Humans, received the Nutrition Research Project of the Year Award. This study showed the impact of 2-HOBA (Hobamine) supplementation on inflammatory biomarkers in

Ingredients for New Age Cellular Health

Author Mike Montemarano from Nutraceuticals World takes a look at ingredients that aim to extend health span from a cellular level. Science continues to evolve on the human body and how there are key markers in human cells and DNA that can give us a better idea on the aging process. With this new knowledge, many specialty ingredients are coming to the forefront to help try to set back our cellular clock. Hallmarks of Biological Age “Even though there is still no consensus about whether aging is biologically programmed, almost all gerontologists agree aging is a clinical disease responsible for

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